Publications
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Distinct regional atrophy in the corpus callosum of patients with temporal lobe epilepsy
Source: Brain 2007 Dec;130:3149-3154.
Author: Weber B, Luders E, Faber J, Richter S, Quesada CM, Urbach H, Thompson PM, Toga AW, Elger CE & Helmstaedter C
PubMed ID: 17728360
Abstract:
We analysed the influence of mesial temporal lobe epilepsy on the thickness of the corpus callosum (CC) in a large sample of well-characterized patients (n=96) and healthy controls (n= 28). In particular, we investigated whether callosal structures are differentially affected depending on the affected hemisphere and age of epilepsy onset.Overall, we observed that epilepsy is associated with a decreased thickness in posterior callosal regions. Patients with an early onset, especially patients with left onset, additionally exhibited a smaller callosal thickness in more anterior andmidbody regions.These findingsmay reflect non-specific as well as specific effects of temporal lobe epilepsy on CC development and interhemispheric connectivity.
Source: Brain 2007 Dec;130:3149-3154.
Author: Weber B, Luders E, Faber J, Richter S, Quesada CM, Urbach H, Thompson PM, Toga AW, Elger CE & Helmstaedter C
PubMed ID: 17728360
Abstract:
We analysed the influence of mesial temporal lobe epilepsy on the thickness of the corpus callosum (CC) in a large sample of well-characterized patients (n=96) and healthy controls (n= 28). In particular, we investigated whether callosal structures are differentially affected depending on the affected hemisphere and age of epilepsy onset.Overall, we observed that epilepsy is associated with a decreased thickness in posterior callosal regions. Patients with an early onset, especially patients with left onset, additionally exhibited a smaller callosal thickness in more anterior andmidbody regions.These findingsmay reflect non-specific as well as specific effects of temporal lobe epilepsy on CC development and interhemispheric connectivity.