About LONI

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“Understanding the brain in all its complexity is impossible for any group to accomplish in isolation.”
-Arthur Toga, Director

We’ve built a diverse team of neurobiologists, mathematicians, and computer scientists, and a worldwide network of collaborators sharing data. Our goal is to increase the pace of discovery in neuroscience by better understanding how the brain works when it’s healthy and what goes wrong in disease.

Our facility houses two advanced Magnetic Resonance Imaging scanners for data acquisition: a Magnetom Prisma 3T and a Magnetom Terra 7T.

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LONI’s onsite data center features state-of-the-art security technology and can store more than four petabytes of brain imaging data.

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Our Scientific Visualization Group creates elegant maps and animations to illustrate brain structure and function.

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Latest News


This fall, the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (INI) received a $2 million competitive renewal from the Alzheimer’s Association to continue expanding its pioneering data-sharing platform, the Global Alzheimer’s Association Interactive Network (GAAIN).


Paul M. Thompson, PhD, has received a Zenith Fellows research grant from the Alzheimer’s Association, one of the most prestigious awards in Alzheimer’s and dementia research.


Most people know that problems with memory and cognition are an early hallmark of Alzheimer’s disease, but fewer are aware that in up to 88% of patients, neuropsychiatric issues like depression, anxiety and apathy are also among the first symptoms of the disease.


Since graduating from the INI’s Master of Science in Neuroimaging and Informatics (NIIN) program, Arvin Saremi (’17) hasn’t slowed down. He has coauthored four journal articles based on research he conducted with the INI’s Neda Jahanshad, PhD, during the master’s program, and is now a medical student at Case Western Reserve University, a top-25 ranked medical school for research.

“The NIIN program opened up many new doors for me—both in terms of opportunity and outlook,” Saremi says. “After exploring neuroimaging, I was able to enter medical school with a clear idea of my career interests from the beginning.”


During his year in the NIIN program, Saremi contributed to research at the INI’s Imaging Genetics Center, studying brain development in children with HIV, genetic markers associated with the volume of the hippocampus, and other topics. He recommends that future students seek out a faculty mentor at the institute and begin conducting research as soon as the program begins.

“The concepts taught in the program are incredibly complex. The best way to learn them is to actively apply them in research,” he says.

Because of the expertise he developed in diagnostic imaging during the NIIN program, Saremi was able to land a position in a neuroimaging lab just weeks after entering medical school. He says he’ll keep an open mind as he moves through the program but ultimately hopes to focus on neuroradiology.

Explore the publications Saremi coauthored during his time at USC:

Altered Cortical Brain Structure and Increased Risk for Disease Seen Decades After Perinatal Exposure to Maternal Smoking: A Study of 9000 Adults in the UK Biobank.

Mapping abnormal subcortical neurodevelopment in a cohort of Thai children with HIV.

Structural Neuroimaging and Neuropsychologic Signatures in Children With Vertically Acquired HIV.

Novel genetic loci associated with hippocampal volume.