“Understanding the brain in all its complexity is impossible for any group to accomplish in isolation.”
-Arthur Toga, Director
We’ve built a diverse team of neurobiologists, mathematicians, and computer scientists, and a worldwide network of collaborators sharing data. Our goal is to increase the pace of discovery in neuroscience by better understanding how the brain works when it’s healthy and what goes wrong in disease.
Our facility houses two advanced Magnetic Resonance Imaging scanners for data acquisition: a Magnetom Prisma 3T and a Magnetom Terra 7T.Learn more
LONI’s onsite data center features state-of-the-art security technology and can store more than four petabytes of brain imaging data.Learn more
Nearly 38 million people around the world are living with HIV, which, with access to treatment, has become a lifelong chronic condition. Understanding how infection changes the brain, especially in the context of aging, is increasingly important for improving both treatment and quality of life.
Until recently, scientists didn’t know much about perivascular spaces (PVS), fluid-filled regions in the brain involved in clearing waste and toxins — mainly because it’s tough to get a clear look at them using neuroimaging. But as technology evolves, researchers are finding that PVS may play a central role in brain changes associated with aging, including in neurodegenerative disorders such as Alzheimer’s disease.
Ryan P. Cabeen, PhD, a postdoctoral researcher in the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (USC Stevens INI) at the Keck School of Medicine of USC, has received an imaging technology grant from the Chan Zuckerberg Initiative (CZI), a philanthropy led by Priscilla Chan, MD, and her husband, Facebook founder Mark Zuckerberg.
Researchers, led by a team at USC, will use artificial intelligence to study tens of thousands of brain images and whole genome sequences.