Publications
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Pontine and cerebellar atrophy correlate with clinical disability in SCA2.
Source: Neurology 2006 Feb;66(3):424-426.
Author: Ying SH, Choi SI, Perlman SL, Baloh RW, Zee DS, Toga AW.
PubMed ID: 16476946
Abstract:
Spinocerebellar ataxia type 2 (SCA2) has protean manifestations, and a clinical marker of progression is needed. Although MRI is a promising tool, it is unclear whether the degree of atrophy shown on MRI is correlated with clinical dysfunction. Here the authors used high-resolution volumetric MRI analysis to show that cerebellar and pontine volumes specifically and closely correlate with functional staging scores.
Source: Neurology 2006 Feb;66(3):424-426.
Author: Ying SH, Choi SI, Perlman SL, Baloh RW, Zee DS, Toga AW.
PubMed ID: 16476946
Abstract:
Spinocerebellar ataxia type 2 (SCA2) has protean manifestations, and a clinical marker of progression is needed. Although MRI is a promising tool, it is unclear whether the degree of atrophy shown on MRI is correlated with clinical dysfunction. Here the authors used high-resolution volumetric MRI analysis to show that cerebellar and pontine volumes specifically and closely correlate with functional staging scores.