A mathematical model and image analysis technique for calculating
regional cerebral blood flow
Source: Computer Methods and Programs in Biomedicine
1989 May;29(1):59-69.
Author: Gitelman DR, Toga AW. PubMed ID: 2714080
Abstract:
This paper discusses the theory and implementation of a modular
data analysis system for the calculation and imaging of regional
cerebral blood flow. The program may be generalized to any system
requiring instantaneous and controllable visual data display, and we
have set it up for compartmental analysis as described by the Fick
equation with certain correction factors. We have included flow charts
of the program source code and data paths for the various modules. We
also describe the functional hardware components necessary for the
execution of these algorithms. Finally, analyzed data are represented
from a set of experiments employing differential visual stimulation. The
results obtained using our methods are comparable to those in the
existing literature; they are more accurately and easily obtained, and
have the added power of manipulable digitization of the original image
without loss of data.