Cerebral glucose metabolic rates in nondepressed patients with obsessive-compulsive disorder

Source: Am J Psychiatry 1988 Dec;145(12):1560-1563.
Author: Baxter LR;Schwartz JM;Mazziotta JC;Phelps ME;Pahl JJ;Guze BH;Fairbanks L
PubMed ID: 3264118

Abstract:
The authors compared 10 nondepressed patients with obsessive-compulsive disorder with 10 normal control subjects of the same sex and similar age for cerebral glucose metabolic rates obtained using positron emission tomography. Obsessive-compulsive patients showed significantly elevated metabolic rates in the whole cerebral hemispheres, heads of the caudate nuclei, orbital gyri, and the orbital gyri relative to the ipsilateral hemisphere (the orbital-hemisphere ratio). These results are similar to those the authors reported previously for another group of obsessive-compulsive patients and normal control subjects