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Broca's Region

Source: International Brain Research Organization 2003;.
Author: Amunts K.

Abstract:
Broca’s region was the first brain region to which a circumscribed function, i.e. language, was linked. Its discovery can be interpreted as the beginning of the scientific theory of the localization of cortical functions. The term originates from anatomo-clinical observations of patients with brain lesions and subsequent disturbances of articulated language, carried out by Pierre Paul Broca (1824-1880) in the middle of the nineteenth century (Broca, 1861a, b; 1863; 1865, Figure 1). A few years after Broca’s first studies, Wernicke (1848-1904) proposed the first theory of language, which postulated an anterior, motor speech centre (Broca’s region), a posterior, semantic language centre (Wernicke’s region), as well as a fibre tract, the arcuate fasciculus, connecting both regions (Wernicke, 1874). Some decades later, Brodmann’s famous maps (1903a, b; 1906; 1908; 1909; 1910; 1912) proposed that cytoarchitectonically defined cortical areas in the inferior frontal gyrus could be the anatomical correlates of Broca’s region.