“Understanding the brain in all its complexity is impossible for any group to accomplish in isolation.”
-Arthur Toga, Director
We’ve built a diverse team of neurobiologists, mathematicians, and computer scientists, and a worldwide network of collaborators sharing data. Our goal is to increase the pace of discovery in neuroscience by better understanding how the brain works when it’s healthy and what goes wrong in disease.
Our facility houses two advanced Magnetic Resonance Imaging scanners for data acquisition: a Magnetom Prisma 3T and a Magnetom Terra 7T.Learn more
LONI’s onsite data center features state-of-the-art security technology and can store more than four petabytes of brain imaging data.Learn more
Mapping the brain's unknown territories and vibrant connections
It’s common knowledge that our surroundings affect our health — decades of research have linked things like air, water and soil quality to various measures of physical well-being. But much less is known about how the environment changes our brain. Now, a research team at the Keck School of Medicine of USC is pooling thousands of brain scans to better understand how aspects of our physical space — including air pollution, noise and green space — alter brain structure, influence our behavior and impact our risk for various developmental, neurodegenerative and psychiatric problems.
A stroke occurs when a blocked artery can no longer supply blood to part of the brain. But the mechanism differs between thrombotic strokes, embolic strokes, thromboembolic strokes, and brain hemorrhages. Our latest scientific visualization describes various types of strokes and illustrates what’s going on in the brain when they occur.
Two new studies, published in Nature Medicine and Movement Disorders, have shown that people with Parkinson disease (PD) exhibit alterations in brain lymphatic and glymphatic drainage systems. The findings suggest that dysfunction of brain drainage pathways represents both an early biomarker and a potential therapeutic target for PD.