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10/08/2018

Researchers show structures, nerve connections and functions in vivid detail as part of the most detailed atlas yet of a person’s memory ban

10/04/2018

Peer support group started by students for students lifts those who want a conversation with someone their own age.

09/26/2018

In fiscal year 2017-2018, the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (INI) at the Keck School of Medicine of USC received more than $30.5 million in active research funding.

09/01/2018

A new preprint called “A systematic bias in DTI findings” could prove worrying for many neuroscientists. In the article, authors Farshid Sepehrband and colleagues of the University of Southern California argue that commonly-used measures of the brain’s white matter integrity may be flawed.

08/23/2018

Two-thirds of AD patients are women, leading to the commonly held assumption that women run a higher risk of dementia. In Chicago, Arthur Toga of the University of Southern California, Los Angeles, challenged that view with data gleaned from a meta-analysis of 58,000 participants in 27 AD studies.

08/23/2018

USC offers numerous institutional training opportunities for postdocs, including parallel lines of research on aging and Alzheimer’s disease. But the new project, “Training for the Multiscale and Multimodal Analysis of Biomarkers in Alzheimer’s Disease,” differs from a traditional postdoctoral fellowship in its highly collaborative nature and its emphasis on both the informatics behind Alzheimer’s research and the use of multiple methodologies to study the disease.

08/21/2018

The Virtual Brain Segmenter turns a tedious step in the scientific process into an immersive experience

07/30/2018

A new virtual-reality (VR) software to correct segmentation errors on MRI scans was found to be faster, more accurate and enjoyable compared to a more commonly used system, report authors of a recent Journal of Digital Imaging study.

10/18/2018

The Virtual Brain Segmenter (VBS), a virtual reality tool for processing brain scan images, has been named a finalist for the 2018 Auggie Breakthrough Awards, which honor innovative academic-industry collaborations in virtual and augmented reality.

VBS was developed by INI’s Dominique Duncan, PhD, Tyler Ard, PhD, Arthur W. Toga, PhD and the industry group RareFaction Interactive to transform a tedious step in the scientific process into an immersive experience. After collecting MRI data, researchers typically correct errors in scan images by hand, but VBS allows them to speed up the process with a VR headset, joystick and larger-than-life images of the brain.

In an experimental trial, published in the Journal of Digital Imaging in July, participants finished a correction task 68 seconds faster using VBS compared with the traditional method, a highly significant time savings considering the task rarely took more than three minutes to complete.

Now, Dr. Duncan is traveling in Munich, Germany to represent INI at the Auggie Breakthrough Awards ceremony, where winners will be chosen in several categories, including Most Innovative Breakthrough, Most Impactful Breakthrough and Best in Show. Fellow finalists include representatives from NASA’s Jet Propulsion Laboratory, Stanford, the Mayo Clinic and international collaborators from Finland, Australia and beyond. Projects span the health sciences, communications, education, resource management and gaming.


Read more about the finalists in the official press release

Learn more about VBS from USC News


08/31/2018

Earlier this month, six undergraduate students from California State University, Fullerton presented their summer research results to a room full of neuroscientists at the Mary and Mark Stevens Neuroimaging and Informatics Institute (INI). The collaboration is part of CSUF’s Big Data Discovery and Diversity through Research Education Advancement and Partnerships (BD3 REAP) program, which trains underrepresented students in big data science.


“The program exposes these young investigators to what modern science is about these days, which is the collection of ever larger data sets,” said Jack Van Horn, INI’s director of education and leader of the collaboration. “They’re learning about the challenges of big data, and how they can manage, model, and understand it.”


Building on several semesters studying data science and analytics at CSUF, each student selected a big data neuroimaging project to pursue this summer with the guidance of INI faculty members and postdoctoral researchers. 


For their presentations, the students covered methods, results and next steps. Each created a slideshow and was encouraged to delve into the technical aspects of research performed. Focus areas included the Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx), using gene expression to build an atlas of the hippocampus and the link between functional brain connectivity and familial Alzheimer’s disease.



The students received mentorship from INI faculty, including program director Jack Van Horn, Kay Jann, Tyler Ard, Dominique Duncan, Lirong Yan and Meredith Braskie.


“This has been a great opportunity for INI to expand its commitment to training the next generation of leaders,” said Arthur W. Toga, provost professor at USC and director of INI. “We were impressed by the students’ work and look forward to continuing our outreach efforts with CSU Fullerton.”

Above, the CSU Fullerton students and their INI mentors.

07/31/2018

Ryan Cabeen, postdoctoral scholar at the Mark and Mary Stevens Neuroimaging and Informatics Institute, has won the International Symposium on Biomedical Imaging's 2018 VoTEM challenge for 3-D tractography.


Cabeen's winning visualization, shown above, depicts neural connectivity in the squirrel monkey and macaque. His work helps reconstruct fiber bundles, a challenge of diffusion MRI, in both phantoms and brain tissue. Below, Cabeen with one of the coolest trophies we've ever seen.

For more information about the VoTEM challenge, visit my.vanderbilt.edu/votem



04/25/2018

For years, the Mark and Mary Stevens Neuroimaging and Informatics Institute (INI) has been a key contributor to the Autism Center for Excellence (ACE) Network, which aims to advance autism research by studying brain structure and aggregating and sharing data. Jack Van Horn, associate professor of neurology at the Keck School of Medicine of USC, directs ACE’s coordinating center.

Van Horn, along with INI’s Zachary Jacokes and Carinna Torgerson and Andrei Irimia of the USC Davis School of Gerontology, recently published an MRI study of the disorder in Nature Scientific Reports. The researchers studied brain structures of autism patients versus healthy individuals, comparing males and females; they found that sex differences in ASD appear to be linked to differences in white matter, specifically in parts of the temporal and parietal lobes. The results are an important step toward understanding why ASD is almost four times more common in boys than girls.

Now, INI researchers are also one step closer to understanding how autism affects the human brain across the lifespan. This month, one of the largest-ever brain morphometry studies of autism, led by the Enhancing Neuro Imaging Genetics through Meta-Analysis autism spectrum disorders working group (ENIGMA-ASD), was published in the American Journal of Psychiatry.

INI’s Paul M. Thompson, director of the Imaging Genetics Center and principal investigator of ENIGMA, and Neda Jahanshad, assistant professor of neurology, contributed to the study.

“Autism is hard to treat because we lack a deep understanding of how children with autism develop differently, and how best to nurture their brain development,” said Thompson. 

“With our global alliance—now studying thousands of children across the world—we are starting to see distinctive brain features in children with autism, and learn how the brain adapts throughout life; we are beginning to have the power to rigorously test and verify factors that may be beneficial for different children.”

The study analyzed MRI scans to identify differences in cortical and subcortical structures between 1,571 patients with ASD and 1,651 healthy controls. Participants from 49 different imaging centers, aged 2 to 64, were included in the analysis. Researchers examined differences in subcortical volumes, cortical thickness and surface area.

ASD subjects had smaller volumes in several brain structures, including the pallidum, putamen, amygdala and nucleus accumbens; they also had decreased cortical thickness in the temporal cortex and increased thickness in the frontal cortex. Cortical development appeared to be most impacted during adolescence, when large differences in thickness were observed. The analysis has led to the first definitive maps of the affected brain regions.

The ENIGMA consortium performs some of the largest neuroimaging studies of rare genetic diseases and psychiatric disorders such as schizophrenia and bipolar disorder, focusing on the interaction between brain health and genetics. The group currently investigates 22 diseases, with researchers in 37 countries analyzing data from more than 53,000 subjects.

03/26/2018

Elegant visualizations of neuroscience data and phenomena are meant to help researchers better understand the brain, but these eye-catching images also have artistic value. This quarter, two of the USC Mark and Mary Stevens Neuroimaging and Informatics Institute’s (INI) visualization specialists, Jim Stanis and Tyler Ard, contributed images to an on-campus exhibition, Neurological System Art.


Stanis, INI’s in-house medical and scientific animator, created “Synaptogenesis,” an image that shows neurons in the brain forming new connections: axons of each neuron grow to synapse with the dendritic spines on the dendrites of other neurons. Stanis used 3DS Max—an animation software package originally built to create visual effects for TV and film—to create 3D models of neurons and to animate the growth of dendrites and axons.


Ard, assistant professor of research at INI, created “Connected Self” using data from fellow INI assistant professor Yonggang Shi. The image shows two different MRI scans of the same subject, highlighting the axons that connect various parts of the brain to one another. Connectivity was measured with a technique called diffusion MRI tractography; different colors represent the orientation of axons in the brain.


Their work appears alongside two featured artists: J. Frederic May and Jane Szabo. In 2012, May suffered a severe stroke during open heart surgery, leaving him legally blind and experiencing visual hallucinations. He uses a data corruption software to create blurry and fragmented images that simulate his visual experience. Szabo has prosopagnosia, or face blindness, and explores self-portraiture and identity through her work. She received her MFA from the Art Center College of Design in Pasadena.


The exhibit is currently on display at the Hoyt Gallery in the Keith Administration Building (KAM).

"Synaptogenesis" by Jim Stanis

"Connected Self" by Tyler Ard

03/09/2018

USC Mark and Mary Stevens Neuroimaging and Informatics Institute (INI) researchers have used machine learning to determine key sex differences in Magnetic Resonance Imaging data in a new study published online ahead of print in NeuroImage. Part of INI's Big Data for Discovery Science initiative, the study analyzed brain scans of more than 1500 healthy youths.


Researchers found that cortical thickness in two areas of the brain-the middle occipital lobes and the angular gyri-are major predictors of sex. Specifically, females demonstrate significantly thicker gray matter in these areas when multiple regions were included in the sex difference model. The team also developed a statistical learning model that accurately predicted sex based on brain morphology in more than 80 percent of participants.


"If we can establish a better understanding of sex differences in the brain, we'll be one step closer to personalized medicine," says Farshid Sepehrband, PhD, project specialist at INI and lead author of the paper. "Once we have a baseline of neuroanatomical sex differences, we can start to explore how and why some diseases-for example, autism-manifest differently in boys and girls." Understanding the anatomic differences between male and female brains could help doctors better diagnose and treat autism in the future.


The study was a collaborative effort among USC researchers, including INI's Sepehrband, Kirsten Lynch, Ryan Cabeen, Lu Zhao, Kristi Clark and Arthur W. Toga. USC faculty from the Viterbi School of Engineering's Information Sciences Institute and the Keck School of Medicine of USC's departments of pediatrics and preventive medicine also contributed to the research, along with Ivo Dinov, PhD, of the University of Michigan.


The code from the study is open-source and public via Github, where users can generate the same figures published in the paper. Sepehrband also used Plotly to generate an interactive plot of the results: hover over each plot point to see the sex difference statistics.


Manuscript: https://doi.org/10.1016/j.neuroimage.2018.01.065

Source codes (Github):https://github.com/sepehrband/Mining_NeuroAnat

Interactive plot (Plotly): https://plot.ly/~sepehrband/50/neuroanatomy-of-sex-difference/

03/01/2018

Judy Pa of Laboratory of Neuro Imaging (LONI)  at Keck Medicine of USC  and Skip Rizzo of USC Institute for Creative Technologies went LIVE on February 27 to discuss the use of virtual reality (VR) and artificial intelligence (AI) to rewire our brains so we can stay healthy.


02/01/2018

The ENIGMA consortium was featured in Science Magazine, including the recent work of Paul Thompson, Chris Whelan and Sanjay Sisodiya. The latest study has identified key structural similarities across all major types of epilepsy, and is already starting to change how researchers think about the disorder.

Science Magazine article: http://www.sciencemag.org/news/2018/01/world-s-largest-set-brain-scans-are-helping-reveal-workings-mind-and-how-diseases

USC News article: http://hscnews.usc.edu/study-all-major-types-of-epilepsy-found-to-share-structural-patterns-in-the-brain/


USC News,

07/25/2018

The Mark and Mary Stevens Neuroimaging and Informatics Institute’s research will let clinicians evaluate the effectiveness of cell-based therapies used to treat various cancers Additional coverage for this study can be found at Health Imaging: https://www.healthimaging.com/topics/molecular-imaging/mri-enhances-cells-determine-effectiveness-therapy

https://news.usc.edu/145890/mri-resolution-enhanced-at-cellular-level-in-breakthrough-usc-study/

HSC News,

05/03/2018

One of the largest-ever brain morphometry studies of autism, led by the Enhancing Neuro Imaging Genetics through Meta-Analysis autism spectrum disorders working group (ENIGMA-ASD), was published in the American Journal of Psychiatry in April.

https://hscnews.usc.edu/global-study-reveals-altered-brain-structure-in-autism/

HSC News,

05/01/2018

Most 8-year olds care more about toys and video games than neuropsychology — but not Joy Stradford. She often went to work with her mother, a special education teacher in New Jersey, and was both concerned for and intrigued by the disabled children she met.

https://hscnews.usc.edu/commencement-2018-spotlight-on-joy-stradford-keck-school-of-medicine-of-usc/

The San Diego Union-Tribune, San Diego Union Tribune

04/22/2018

A large number of people taking medications for Alzheimer's actually might not have the disease, according to early evidence from a study presented Wednesday. But detection may become easier if an experimental blood test ultimately proves accurate, said another report released on the same day.

http://www.sandiegouniontribune.com/business/biotech/sd-me-alzheimers-screening-diagnosis-20170719-story.html

USC News,

03/23/2018

Keck School of Medicine of USC surgeon and radiologist team up to test a new ultrahigh field imaging technology

https://news.usc.edu/138735/new-mri-scanner-may-revolutionize-diagnosis-and-treatment-of-brain-tumors/

HSC News,

03/06/2018

On Feb. 3, local teens converged on USC’s Health Sciences Campus for the Los Angeles Brain Bee, a day of exploration, networking and competition.

https://hscnews.usc.edu/brain-bee-brings-aspiring-neuroscientists-to-campus/

USC News,

02/21/2018

Brain scans from stroke patients are being downloaded by researchers around the world to predict the most efficient therapies

https://news.usc.edu/136878/database-brain-images-big-data-to-boost-stroke-recovery/

USC News,

02/14/2018

Consortium looks at biological factors that can predict health outcomes as part of a five-year study

https://news.usc.edu/136129/usc-joins-national-group-in-search-for-signs-of-onset-dementia/

USC News,

02/02/2018

Thousands of brain scans are studied to better understand patterns of differences in one of the largest imaging studies to date

https://news.usc.edu/135235/multiple-forms-of-epilepsy-share-similar-underpinnings-study-finds/

HSC News,

01/26/2018

Paul Thompson, PhD, associate director of INI, has received a NARSAD Distinguished Investigator Grant from the Brain & Behavior Research Foundation (BBRF) for his work on sex disparities in mental health.

https://hscnews.usc.edu/keck-school-professor-receives-distinguished-investigator-grant-for-mental-health-research/

Data Skeptic, N/A

01/23/2018

LONI was featured in a two-part episode about how researchers are using data science to study the brain. The series covers the latest updates in data collection, brain imaging, LONI Pipeline, artificial intelligence and current challenges in the field. Hear from Director Arthur W. Toga, Professor Meng Law, and researchers Farshid Sepehrband and Ryan Cabeen.

https://dataskeptic.com/blog/episodes/2018/neuroimaging-and-big-data

https://dataskeptic.com/blog/episodes/2018/neuroscience-frontiers

Spectrum News,

11/15/2017

Tyler Ard has created a new visualization tool, Neuro Imaging in Virtual Reality, that enables researchers to interact with large neuroimaging data sets in a new way. The intuitive software enables users to view, segment, and even virtually dissect the brain. Ard's presentation at the 2017 Society for Neuroscience annual meeting was featured in Spectrum.

https://spectrumnews.org/news/technology-harry-potter-movies-brings-brain-focus/

USC News,

11/10/2017

The National Institutes of Health-funded research at several departments will use existing data to explore the issue

https://news.usc.edu/130284/big-data-study-at-usc-to-investigate-link-between-gender-and-alzheimers-risk/

USC News, Zara Abrams

10/18/2017

Arthur W. Toga joins other researchers on the five-year study backed by a $12 million grant from the National Institutes of Health. Researchers at the USC Stevens Neuroimaging and Informatics Institute will process 4,000 brain scans during the study.

https://news.usc.edu/129588/usc-seeks-a-better-understanding-of-alzheimers-among-mexican-americans/

CNET,

10/15/2017

On October 15, CNET highlighted Dr. Sook-Lei Liew's Rehabilitation Environment using the Integration of Neuromuscular-based Virtual Enhancements for Neural Training (REINVENT), which is used to treat patients who have suffered severe strokes. The brain-computer interface uses virtual reality to promote brain plasticity.

https://www.cnet.com/news/vr-could-trick-stroke-victims-brains-toward-recovery/

Medical News Today,

08/29/2017

On Aug. 29, Medical News Today spotlighted a study by Scott Neu, PhD, assistant professor of research neurology, Arthur Toga, PhD, Provost Professor of ophthalmology, neurology, psychiatry and the behavioral sciences, radiology and engineering and Ghada Irani Chair in Neuroscience, and Judy Pa, PhD, assistant professor of neurology, that found that women with a genetic predisposition for Alzheimer's disease have a higher risk of developing the disease between ages 65 and 75 than men.

http://www.medicalnewstoday.com/articles/319164.php?MassEmailID=322924503&email_id=1&emailaddress=All-KSOM-Staff-L@usc

Health Day

08/28/2017

On Aug. 28, HealthDay spotlighted a study by Scott Neu, PhD, assistant professor of research neurology, Arthur Toga, PhD, Provost Professor of ophthalmology, neurology, psychiatry and the behavioral sciences, radiology and engineering and Ghada Irani Chair in Neuroscience, and Judy Pa, PhD, assistant professor of neurology, that found that women with a genetic predisposition for Alzheimer's disease have a higher risk of developing the disease between ages 65 and 75 than men.

https://consumer.healthday.com/cognitive-health-information-26/alzheimer-s-news-20/women-at-risk-f

USC Trojan Family Magazine

07/12/2017

A new Alzheimer's disease study examines how cognitive and physical activity can help brains stay healthy.

https://tfm.usc.edu/can-brain-activity-and-exercise-delay-alzheimers-disease

USC News

04/05/2017

Arthur Toga saw the disease ravage his family, so he's worked to transform what scientists know and think about the memory-erasing illness that affects 1 in 3 seniors.

https://news.usc.edu/119535/the-close-to-home-reason-this-usc-brain-scientist-is-trying-to-figure-out-alzheimers/

Medical Xpress

03/28/2017

An international network of neurologists, geneticists and researchers led by the Keck School of Medicine of USC is cracking the human genetic code so that one day people could check their "brain health" in the same way they screen their cholesterol level.

https://medicalxpress.com/news/2017-03-brain-genetic-code-neurological-psychiatric.html

National Institutes of Health, Dr. Francis Collins

02/07/2017

The human brain contains distinct geographic regions that communicate throughout the day to process information, such as remembering a neighbor’s name or deciding which road to take to work. Key to such processing is a vast network of densely bundled nerve fibers called tracts. It’s estimated that there are thousands of these tracts, and, because the human brain is so tightly packed with cells, they often travel winding, contorted paths to form their critical connections. That situation has previously been difficult for researchers to image three-dimensional tracts in the brain of a living person.

https://directorsblog.nih.gov/

89.3KPCC, Sanden Totten

11/17/2016

On Thursday, the University of Southern California opened the doors to its newest hub of research, the Stevens Hall for Neuroimaging. This state of the art center hopes to foster collaboration between neuroscientists around the world.

http://www.scpr.org/news/2016/11/17/66247/brain-boost-usc-launches-cutting-edge-neuroscience/

ABC7 Eyewitness News

11/02/2016

ABC News Los Angeles affiliate KABC-TV quoted Bradley Williams of the USC School of Pharmacy and Arthur Toga of Keck Medicine of USC about a recent pharmaceutical development in treating Alzheimer's disease.

http://abc7.com/health/new-drug-appears-to-slow-alzheimers-degenerative-process/1586558/

OZY, James Watkins

10/27/2016

The human brain is the most complex computational device in the known universe (for now). It's so powerful that it has managed to design its greatest rival--the supercomputer.

http://www.ozy.com/fast-forward/how-supercomputers-can-map-disease-in-your-brain/71921

USC News

10/10/2016

The USC Laboratory of Neuro Imaging of the USC Mark and Mary Stevens Neuroimaging and Informatics Institute has received a $21.7 million National Institutes of Health grant to study epilepsy, a condition that is currently incurable.

http://news.usc.edu/109286/usc-gets-21-7-million-grant-to-study-epilepsy/

Genetic Engineering & Biotechnology News,

10/06/2016

Whether or not brain size matters is a question that has received only tentative and highly qualified answers. Hoping to be more definite, an international team of scientists addressed the question again, but this time they did so while ensuring their study had something previous studies lacked—size.

http://www.genengnews.com/gen-news-highlights/size-matters-study-reveals-brain-reserve-genes/81253295/

USC News, Zen Vuong

10/05/2016

In the world's largest MRI study on brain size to date, USC researchers and their international colleagues identified seven genetic hotspots that regulate brain growth, memory and reasoning as well as influence the onset of Parkinson's disease.

http://news.usc.edu/109149/does-brain-size-really-matter/

The TeCake

10/05/2016

Medical Theory has come up a long way to curing people from several diseases. With the help of numerous researches and theories, the hypothesis of medical is kept on being more fruitful over time. However, all the studies and tests haven’t yet discovered all the conditions related to psychiatric and neurological issues. The issues of psychiatric and neurological imply to the mental health problems which can top a cluster of disorders, including mental, personality, behaviour, and social interactions. Like physical disorders, psychiatric and neurological issues are a little bit tricky to diagnose precisely, and hence overwhelmed the treatment and healing methods.

http://tecake.in/news/health/electrifying-brain-zapping-reduce-symptoms-psychiatric-check-24274.html

The Economic Times

10/04/2016

Electrifying brain circuits could treat neurological and psychiatric symptoms not because it causes neurons to fire but it creates an environment that makes it more or less likely for neurons to fire, researchers, including one of Indian-origin, have found.

http://economictimes.indiatimes.com/news/science/how-brain-zapping-could-decrease-psychiatric-symptoms/articleshow/54676

Science Daily

10/04/2016

Rather than taking medication, a growing number of people who suffer from chronic pain, epilepsy and drug cravings are zapping their skulls in the hopes that a weak electric current will jolt them back to health. Here's the issue: Until now, scientists have been unable to look under the hood of this DIY therapeutic technique to understand what is happening.

https://www.sciencedaily.com/releases/2016/10/161004090445.htm

The Hill, Arthur W. Toga

09/21/2016

Once a year, the world, politicians and citizens, alike, acknowledge the impact of Alzheimer's disease and the toll it takes on populations worldwide. On this World Alzheimer's day, the thought of ourselves, our families, our collective memories lost to this neurodegenerative disease, are recognized.

http://thehill.com/blogs/pundits-blog/healthcare/297047-world-alzheimers-day-finding-answers-on-advocacy-and-awareness

Mehr News Agency

09/18/2016

Professor Paul Thompson, of Imaging Genetics Center Lab, University of Southern California in Los Angeles, was second speaker of the second day. He is the head of "ENIGMA" and provided information about the project; "ENIGMA" helps our understanding of structure, functions, and brain diseases through data from brain mapping and genetics; three company contribute to the project and so far, more than 50,000 people from 35 countries have participated; the project is in fact convergence of the brain mapping community to establish one of the greatest data bank in the history of science. The ultimate objective is to decode the genetics of the brain,” he told the congress.

More here:

https://en.mehrnews.com/news/119830/Enigma-brings-Iran-major-international-project


Huntington's Disease News, Magdalena Kegel

06/22/2016

New data on an uncharted dark spot of the mouse brain map reveals how connections between brain cells form networks responsible for movement and motor learning — tasks that go awry in conditions such as Huntington’s disease.

http://huntingtonsdiseasenews.com/2016/06/22/mouse-brain-map-to-aid-huntingtons-scientists-focus-efforts/

Science Daily, University of Southern California

06/20/2016

New brain map could enable novel therapies for autism,Huntington's disease

https://www.sciencedaily.com/releases/2016/06/160620120254.htm

HSC News, Keck Net Intranet

04/18/2016

The USC Mark and Mary Stevens Neuroimaging and Informatics Institute (INI) received its new research-dedicated Siemens Magnetom 3T Prisma MRI scanner March 21, bringing industry-leading brain imaging technology to USC’s Health Sciences Campus.

http://hscnews.usc.edu/category/keck-net-intranet/

USC News, Lynn Lipinski

12/25/2015

The USC Mark and Mary Stevens Neuroimaging and Informatics Institute will bring together scientists from around the world to further understanding of the brain. Longtime benefactors Mark and Mary Stevens’ $50 million gift will accelerate the institute’s already dramatic progress toward mapping the healthy brain and illuminating neurologic diseases such as Alzheimer’s and schizophrenia.

http://news.usc.edu/90120/usc-2015-gifts-that-keep-giving/

Keck News, Katharine Gammon

11/08/2015

What would we be able to see, Toga pondered, if we could use computer-enabled imaging to view how the brain works? Toga has devoted his career to answering that question. As director of the USC Mark and Mary Stevens Neuroimaging and Informatics Institute, he has built one of the largest data collections of human brain images in the world. By combining the power of computer science with the study of brain science, his team at the institute—which comprises researchers across disciplines like neuroscience, physics, engineering and math—can map brain image data in an unprecedented way.

http://www.keck.usc.edu/data-on-the-brain-the-power-of-imaging/

USC News, Zen Vuong

10/19/2015

The nation's first Training Coordination Center aims to spot trends among enormous amounts of data.

http://news.usc.edu/87595/usc-to-teach-worldwide-researchers-how-to-analyze-biomedical-information-at-big-data-u/

HSC News, Douglas Morino

10/09/2015

Seeking to strengthen partnerships between two of USC’s oldest schools, scientists from the Keck School of Medicine of USC and USC Dornsife College of Letters, Arts and Sciences recently gathered to discuss new research and areas for future collaboration.

http://hscnews.usc.edu/at-keck-dornsife-retreat-scientists-share-research/

The News & Observer, Malcolm Ritter

06/22/2015

To the untrained eye, it looked like a seismograph recording of a violent earthquake or the gyrations of a very volatile day on Wall Street — jagged peaks and valleys in red, blue and green, displayed on a wall. But the story it told was not about geology or economics.

http://www.newsobserver.com/living/health-fitness/article24878257.html

Keck School of Medicine of USC

06/19/2015

A USC project to visualize and analyze connectivity networks in the mouse brain is among 15 new awards from the National Institutes of Health (NIH) tied to the development of biomedical Big Data applications.

http://www.keck.usc.edu/news/nih-big-data-grant-will-fund-visual-analysis-project/

NIH

06/04/2015

Congratulations to Dr. Hongwei Dong and his team for winning 1 of only 4 BD2K Targeted Software Development awards in the field of Data Visualization.

https://datascience.nih.gov/bd2k/funded-programs/software#Visualization

USC, USC Media Relations staff

03/25/2015

The gift will streamline the translation of basic research into new therapies for brain injury and disease.

http://news.usc.edu/77585/50-million-gift-will-name-the-usc-mark-and-mary-stevens-neuroimaging-and-informatics-institute

LA Times, Larry Gordon

03/25/2015

A Silicon Valley venture capitalist who is a USC alumnus and his wife are donating $50 million to a USC brain research institute in hopes of treating such disorders as Alzheimer’s disease, autism and traumatic brain injuries, university officials announced..

http://www.latimes.com/local/education/la-me-ln-usc-gift-20150325-story.html

Cell

01/01/2015

Professor Hong-Wei Dong leads a team working on an ambitious NIH-funded Mouse Connectome Project at the USC Institute of Neuroimaging and Informatics, Keck School of Medicine of USC. The first major milestone research paper entitled, Neural Networks of the Mouse Neocortex, was published in Cell on Feb, 2014 (Zingg et al., 2014, Cell, 156). This article was selected as one of the Top 10 research articles in Cell: Best of 2014. This paper is also on the full historical "40 years of Cell" time line as one of the only two landmark papers of 2014 (http://www.cell.com/40/timeline). More information on the Mouse Connectome Project can be found at http://www.mouseconnectome.org/.

http://onlinedigeditions.com/publication/frame.php?i=236801&p=&pn=&ver=flex

PR Newswire

10/09/2014

In a rare distinction for one university, neuroimaging world leaders and USC Professors Arthur Toga and Paul Thompson will receive two major research center awards to advance their exploration of the human brain.

http://www.prnewswire.com/news-releases/neuroscientists-claim-rare-pair-of-research-grants-278656591.html

Los Angeles Times, Melissa Healy

10/09/2014

Calling the world's wealth of health data a formidable "engine of discovery," the National Institutes of Health on Thursday awarded $32 million in grants in a bid to make huge biomedical data sets accessible to researchers the world over.

http://www.latimes.com/science/sciencenow/la-sci-sn-big-data-money-20141009-story.html

Science News Magazine, Laura Sanders

07/26/2014

Dr. John Van Horn is quoted in this article: The new study has "direct relevance to our outstanding of major brain disorders", says neuroscientist John Van Horn of the University of Southern California in Los Angeles.

https://www.sciencenews.org/article/busy-brain-hubs-go-awry-disorders-study-suggests?mode=topic&context=69

MD News, Thomas Crocker

07/01/2014

Researchers at the University of Southern California are painstakingly mapping the mouse brain, a project with significant implications for understanding how structures in the human brain communicate and how disruptions in their interactions may affect the development of neurological diseases such as Alzheimer's.

http://viewer.e-digitaledition.com/i/336371

Slate, Sean Kean

05/06/2014

On Sept. 13, 1848, at around 4:30 p.m., the time of day when the mind might start wandering, a railroad foreman named Phineas Gage filled a drill hole with gunpowder and turned his head to check on his men. It was the last normal moment of his life.

http://www.slate.com/articles/health_and_science/science/2014/05/phineas_gage_neuroscience_case_true_story_of_famous_fro

2014 Electrical Excellence Award

04/08/2014

Our (temporary) data center won the 2014 Electrical Excellence Award sponsored by the Los Angeles County Chapter of the National Electrical Contractors Association (NECA). Congrats to the engineers and contractors on this amazing project.


Fox News, Stephanie Pappas

02/28/2014

Glowing new images of the mouse brain represent the most comprehensive mapping yet of the mammalian cortex.

http://www.foxnews.com/health/2014/02/28/beautiful-mouse-brain-map-holds-clues-to-neurological-disease/

MIND Guest Blog, Scientific American, Ben Thomas

02/20/2014

A February 20 story on the MIND Guest Blog featured a comprehensive "roadmap" of the brain's neural connections developed by John Darrell Van Horn, PhD.

http://blogs.scientificamerican.com/mind-guest-blog/2014/02/20/brain-wide-map-of-neural-highways-is-first-of-its-kind/

Frontiers in Human Neuroscience, Zara Abrams

02/11/2014

The journal article entitled "The hubs of the human connectome are generally implicated in the anatomy of brain disorders" was published in Brain on June 19, 2014. A summary of resulting news coverage is listed below.

Scientific American MIND, May 10th, 2014 Issue (interviewed)

National Geographic, May 10th, 2014 (interviewed)

Science News, May 12th, 2014 (interviewed)

USC Annenberg News, May 12th, 2014

iOp.com, May 11th, 2014

Science Daily, February 11, 2014

Article featured on the Frontiersin.org website, February 14th, 2014

Fast Company Design, Shaunacy Ferro

01/10/2014

FastCoDesign.com highlights the progress of the Human Connectome Project in an article entitled "8 Mind-Blowing Images Of The Brain At Work."

http://www.fastcodesign.com/3024528/8-mind-blowing-images-of-the-brain-at-work