Association of Subjective Cognitive Complaints and Objective Cognitive Impairment in Late Life Depression
Source: The American Journal of Geriatric Psychiatry
Author: Ruth Morin, PhD, David D. Bickford, BA, Yiu Ho Au, Bachelor of Science, Kelly B. Scherer, Daniel C. Catalinotto, BA, Philip Insel, Duygu Tosun, PhD, Michelle Zmuda, BS, Arthur W. Toga, Paul S. Aisen, MD, Rema Raman, PhD, Andrew Saykin, Michael Weiner, Meryl A. Butters, Craig Nelson, MD, Scott Mackin, PhD
Major depressive disorder in the elderly (late life depression; LLD) is a disabling psychiatric condition affecting an estimated 8–16% of the older adult population, with a significant impact on public health. The presence of depressive symptoms has also been consistently implicated as a risk factor for dementia due to co-occurrence of cognitive impairments in individuals with LLD and increased rates of conversion to dementia. Recent studies also demonstrate that individuals with LLD report greater concern about their cognitive status relative to older adults without depressive symptoms.